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It was discovered that naltrexone and bupropion combined, that could be marketed later on as Contrave, give better weight loss results than diet and exercise alone.

Using two separate drugs to lose weight can be very effective you will find combinations in front of the FDA now awaiting approval. When dealing with weight loss and the those who go through it one should err assisting caution and allow FDA do its job and demand some study be done so that the public recognizes the side effects and perils associated with the medications before we take them. Keep in mind that drug companies have been in business to generate income and that they would say anything to keep people on his or her medications.

Researchers found that participants taking this drug for any year, lost weight within one month and have kept the load off through the entire 56 weeks from the study. Contrave can be a combination of the drugs naltrexone and bupropion, which usually reflect a brand new trend of weight-loss drugs which are made up of many active ingredient, which might make them more efficient and safer.

Combo-pilling is the newest fad or better yet the newest to come under scrutiny and thus it is just more publicly known lately, comb-pilling for weight reduction has been around since the eighties. The biggest reason that employing a combination of pills has become popular is the fact that since right now there are no long term prescription slimming capsules that have been approved by the FDA apart from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications and some of the combinations happen to be rejected or have yet to be approved by the FDA.

Seizures really are a side effect with Contrave and mustn't be taken in individuals with seizure disorders. The drug could also raise blood pressure levels and heart rate, and really should not be used in people who have a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with the drug.

The FDA also warned that Contrave can raise blood pressure level and heartbeat and must not used in patients with uncontrolled high blood pressure, and also by anyone with heart-related and cerebrovascular (circulation dysfunction impacting the brain) disease. Patients having a history of heart attack or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes with a boxed warning to alert medical researchers and patients to the increased chance of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stopping smoking.


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